androgen receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10320	Androgen receptor antagonist 1		Others
	Androgen receptor antagonist 1 is an orally available full androgen receptor antagonist (IC50: 59 nM). It can be used in the synthesis of PROTAC AR degraders, which results in 24% and 47 % AR protein degradation in LNCaP...		Others
T0380	Bicalutamide	ICI-176334	Androgen Receptor , Autophagy
	Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.		Androgen Receptor , Autophagy
T9035	Testosterone undecanoate		Others , Androgen Receptor
	Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.		Others , Androgen Receptor
T22263	Bavdegalutamide	ARV-110	Androgen Receptor
	Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati...		Androgen Receptor
T60988	Androgen receptor antagonist 4
	Androgen receptor antagonist 4 (Compound AT2) has anticancer activities. Androgen receptor antagonist 4 potently antagonizes the activity of AR transcriptional, inhibits downstream target gene of AR, and blocks the DHT-i...
T80633	Androgen receptor degrader-1		Androgen Receptor
	Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].		Androgen Receptor
T60987	Androgen receptor antagonist 3
	Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].
T12928	SK33		Androgen Receptor
	SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.		Androgen Receptor
T79024	Androgen receptor-IN-5		Androgen Receptor
	Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and INF-γ.		Androgen Receptor
T83119	Androgen receptor antagonist 9		Androgen Receptor
	Androgen Receptor Antagonist 9 (compound 28) serves as an antagonist to the androgen receptor [1].		Androgen Receptor
T63324	Androgen receptor antagonist 5
	Androgen receptor antagonist 5 is a potent antagonist of the androgen receptor (AR) (IC50: 6.17 μM). Androgen receptor antagonist 5 inhibited the proliferation of prostate cancer cells LNCaP and showed antitumor effect i...
T80647	Androgen receptor degrader-2		Androgen Receptor
	Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].		Androgen Receptor
T79891	Androgen receptor degrader-3		Androgen Receptor
	Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potential applications in prostate cancer research [1].		Androgen Receptor
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T14116	ACP-105		Androgen Receptor
	ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.		Androgen Receptor
T13272	UT-155		Androgen Receptor
	UT-155 is a selective and potent antagonist of the androgen receptor (AR) (Ki: 267 nM for UT-155 binding to AR-LBD).		Androgen Receptor
T12323	ORM-15341		Androgen Receptor
	ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)		Androgen Receptor
T14008	2,2,5,7,8-Pentamethyl-6-Chromanol	PMC	Androgen Receptor
	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.		Androgen Receptor
T20625	Prochloraz	Sporgon,Prelude	Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal
	Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and...
T7690	2-hydroxy Flutamide		Androgen Receptor
	2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer		Androgen Receptor